Keep the soil consistently moist but not waterlogged. Allow the top inch of soil to dry slightly between waterings. Reduce watering during the dormant period in fall and winter to prevent root rot.

Ensure good drainage to avoid standing water.

Remove any yellowing or dead leaves as they appear to maintain the plant's aesthetic appeal and direct energy towards healthy growth. Trim away spent flower stalks if present, though Caladiums are primarily grown for their foliage and flowers are often insignificant.

Caladium humboldtii can be propagated by dividing the tubers during repotting. Ensure each division has at least one eye or growing point.

Plant the divisions in well-draining potting mix and keep them warm and moist until new growth emerges.

Repot your Caladium humboldtii annually or every other year in the spring, or when the tubers have filled the pot. Choose a pot that is slightly larger than the current one and use a well-draining potting mix.

This is also an ideal time to divide tubers.