Picris hispanica prefers well-drained soil and tolerates drought once established. Water moderately during the growing season, allowing the soil to dry out slightly between waterings.

Reduce watering significantly in winter to prevent root rot. Avoid overwatering, as it can lead to fungal diseases.

Pruning is typically minimal for Picris hispanica. Deadhead spent flower stalks to encourage further blooming and maintain a tidy appearance.

In late autumn or early spring, remove any dead or damaged foliage to promote new growth. Avoid heavy pruning unless absolutely necessary to shape the plant.

Picris hispanica can be propagated by seeds sown in early spring or autumn. The seeds germinate best with light stratification. It can also be propagated by division of established clumps in early spring.

Ensure divisions have adequate root systems before replanting.

Repotting is generally not a common requirement for Picris hispanica, as it is often grown as an annual or biennial, or in established garden beds.

If grown in a container and it becomes root-bound, repot in spring to a slightly larger pot using a well-draining potting mix. This is usually only necessary every 2-3 years.