Water sparingly, allowing soil to dry out completely between waterings. Overwatering is a common cause of root rot. In humid climates, reduce watering frequency.

Ensure good drainage to prevent waterlogged conditions, which this plant dislikes.

Pruning is generally not required for Euphorbia ophthalmica. If necessary, trim to maintain shape or remove any dead or damaged stems.

Use clean, sharp tools and avoid over-pruning, as it can stimulate excessive sap production.

Propagate by stem cuttings. Allow cuttings to callus for a few days before planting in well-draining soil. Rooting is typically successful in warm conditions with bright, indirect light. Avoid contact with the sap.

Repot only when necessary, typically every 2-3 years, or when the plant outgrows its container. Use a well-draining succulent or cactus mix. Choose a pot only slightly larger than the previous one. Repot in spring.