Water regularly, especially when the plant is establishing. Once established, Mexican Fleabane is quite drought-tolerant. Allow the soil to dry out slightly between waterings, but avoid prolonged dryness.

Overwatering can lead to root rot, so ensure good drainage.

Deadhead spent flowers regularly to encourage more blooms and maintain a tidy appearance. At the end of the growing season, or in early spring before new growth begins, cut the plant back by about half to prevent it from becoming too leggy and to promote a bushier habit.

Mexican Fleabane is easily propagated by seed sown in spring or by division of established clumps in spring or autumn. Cuttings taken in late spring or early summer will also root readily in moist soil or a seed-starting mix.

Repot young plants annually in spring into slightly larger containers. Established plants in the ground rarely need repotting.

If grown in pots, repot when the roots begin to fill the container, typically every 1-2 years, to provide fresh soil and space for root growth.