Water Bridelia cathartica regularly, keeping the soil consistently moist but not waterlogged. Allow the top few centimeters of soil to dry out slightly between waterings, especially during dry periods.

Reduce watering in cooler months to prevent root rot.

Prune Bridelia cathartica to maintain its shape and size, or to remove any dead, diseased, or crossing branches. Light pruning can be done anytime, while heavier pruning is best done in late winter or early spring before new growth emerges.

Propagate knobbly sweetberry from semi-hardwood cuttings taken in summer or from seeds sown in spring. Cuttings should be treated with rooting hormone and placed in a well-draining medium in a warm, humid environment.

Repot young plants every 1-2 years, and mature plants every 3-4 years, or when root-bound. Use a well-draining potting mix. Repotting is best done in spring before the active growing season begins.