California cudweed prefers well-draining soil and is drought-tolerant once established. Water moderately during the initial growth phase, allowing the soil to dry out slightly between waterings.

Reduce watering in cooler months and avoid waterlogging, which can lead to root rot.

Prune to maintain shape and encourage bushier growth. After flowering, you can deadhead spent blooms to prevent self-seeding if desired.

Light pruning can also be done in early spring to remove any dead or damaged foliage from the previous season.

California cudweed can be propagated by seeds or stem cuttings. Sow seeds in early spring, either directly outdoors or in a nursery bed.

Stem cuttings can be taken in late spring or early summer and rooted in well-draining soil or a suitable medium.

Repotting is typically not a frequent requirement for Pseudognaphalium californicum, as it prefers to be slightly root-bound. If it becomes necessary, usually for container-grown plants that have outgrown their pot, repot in spring into a slightly larger container with fresh, well-draining potting mix.