Water moderately when the top 2-3 cm of soil feels dry. Ensure good drainage to prevent waterlogging, as Calycophyllum megistocaulum dislikes consistently wet roots.

Reduce watering in cooler months, allowing the soil to dry out more between waterings.

Prune to maintain shape and remove any dead, damaged, or crossing branches. Light pruning can be done any time of year, but heavier pruning is best done in late winter or early spring before new growth begins.

Use clean, sharp tools.

Propagation is typically done through seeds, which require stratification and consistent warmth for germination. Stem cuttings can also be attempted, but success rates may vary.

Rooting hormone may improve success with cuttings.

Repot every 2-3 years or when the plant becomes root-bound, preferably in spring. Use a well-draining potting mix. Choose a pot that is only slightly larger than the current one to avoid overwatering issues.