Water moderately during the growing season, allowing the soil to dry out slightly between waterings. Reduce watering significantly in winter to prevent root rot.

Ensure well-draining soil to avoid waterlogging, especially for young plants.

Pruning is typically not required for Bieberstein's thistle beyond removing dead or damaged foliage. If the plant becomes unwieldy, cut back stems after flowering to maintain shape and prevent excessive seed spread.

Propagate Bieberstein's thistle by seed sown in autumn or early spring. Stratification may improve germination rates. Division of established clumps in spring is also a viable method, though less common.

Repotting is generally not necessary for established plants as they prefer to be in their native, often poor, soil conditions. If starting from seed or a small division, use a well-draining potting mix and repot when roots fill the container.