Luffa acutangula requires consistent and ample watering, particularly once flowers and fruits begin to develop. Maintain evenly moist soil, but ensure good drainage to prevent waterlogging, which can lead to root rot. Reduce watering slightly as fruits mature towards harvest.

Pruning is essential for managing the vigorous growth of Luffa acutangula and enhancing fruit yield. Pinch back the main stem once it reaches a desired length (e.g., 2-3 meters) to encourage lateral branching. Regularly remove any yellowing, diseased, or unproductive leaves and branches. Thinning out excess fruits can also help the plant direct energy into developing larger, higher-quality gourds.

Luffa acutangula is primarily propagated from seeds. Sow seeds directly into warm soil after the last frost, or start indoors 3-4 weeks before transplanting. Scarifying seeds or soaking them in warm water for 24 hours can improve germination rates, which typically occur within 7-14 days.

As an annual vine typically grown directly in the ground or large containers, repotting is not a standard practice for Luffa acutangula. If starting seeds in small pots, transplant seedlings to their final growing location once they have developed a few true leaves and outdoor conditions are suitable.