Water sparingly, allowing the soil to dry out completely between waterings. Hyobanche fulleri is adapted to arid conditions, making overwatering the most common cause of failure.

Ensure excellent drainage to prevent root rot.

Pruning is typically not necessary for Hyobanche fulleri, as it is an ephemeral or short-lived herbaceous plant. Remove any dead or spent flowering stalks only after the plant has finished its life cycle.

Propagation is primarily achieved through seed. Collect seeds from mature pods and sow them on moist, well-draining soil.

Germination is often erratic and may require specific conditions or the presence of a suitable host plant's roots.

Repotting is not a standard practice for Hyobanche fulleri, as it is often grown from seed and has a short lifespan. If attempting to grow it long-term, ensure it is planted in a substrate that mimics its natural, free-draining habitat.