Datura innoxia prefers consistent moisture, especially during dry periods and flowering. Water deeply when the top few centimeters of soil feel dry, but avoid waterlogging, which can lead to root rot.

Established plants show some drought tolerance, but regular watering promotes vigorous growth and abundant blooms. Reduce watering slightly in cooler weather.

Pruning Datura innoxia is not strictly necessary but can be beneficial for maintaining its desired shape and size.

Lightly prune to encourage a bushier habit or to remove spent flowers (deadhead) to promote continuous blooming. Always wear protective gloves when handling this plant due to its high toxicity.

Remove any dead, damaged, or diseased branches promptly to maintain plant health and appearance throughout the growing season.

Datura innoxia is easily propagated from seeds. Sow seeds directly outdoors after the last frost or start them indoors 6-8 weeks prior. Seeds typically germinate within 2-4 weeks.

Cuttings can also be rooted, though this is less common. Ensure good drainage and warmth for successful germination and rooting.

If grown in pots, Datura innoxia may require repotting annually into a slightly larger container to accommodate its fast growth and extensive root system.

Choose a pot with good drainage and use a well-draining potting mix. Repot in spring before new growth begins. Handle with care due to toxicity.