Datura stramonium needs regular watering, especially during dry periods and when flowering, to maintain consistently moist soil. Ensure good drainage to prevent root rot.

Reduce watering as temperatures cool in late autumn.

Pruning for Datura stramonium is generally minimal as it's an annual. Deadheading spent flowers is recommended to promote continuous blooming and prevent unwanted self-seeding.

Pinching back young plants can encourage a bushier, more compact growth habit. Always wear protective gloves when handling this plant due to its high toxicity.

Datura stramonium is most commonly propagated from seeds. Seeds can be directly sown outdoors after the last frost, or started indoors 6-8 weeks prior to the anticipated transplant date.

Light scarification or a period of cold stratification can significantly improve germination rates. Ensure seedlings are hardened off before transplanting outside.

As an annual plant, Datura stramonium typically does not require repotting in the traditional sense. It is usually grown from seed each year.

If started indoors in small containers, seedlings should be transplanted to their final outdoor location in the garden or a larger pot once they have developed a few true leaves and all danger of frost has passed.