Water Oxypetalum appendiculatum moderately during the growing season, allowing the soil to dry slightly between waterings. Reduce watering significantly in winter to prevent root rot.

Ensure good drainage to avoid waterlogged conditions, which this plant dislikes.

Prune Oxypetalum appendiculatum in late winter or early spring to shape the plant and remove any dead or damaged stems. Light pinching can encourage bushier growth.

Pruning also helps maintain plant vigor and promotes better flowering.

Propagate Oxypetalum appendiculatum from semi-hardwood cuttings taken in summer. Root the cuttings in a well-draining potting mix, keeping them moist and in a warm, humid environment.

Seed propagation is also possible but may be slower.

Repot Oxypetalum appendiculatum every 2-3 years in spring, or when root-bound. Use a well-draining potting mix.

Choose a pot that is only slightly larger than the previous one to avoid excessive moisture retention, which can be detrimental.