Allow the soil to dry out completely between waterings. Euphorbia aphylla is drought-tolerant and susceptible to root rot if overwatered.

Water sparingly in cooler months, typically reducing frequency significantly during winter dormancy. Ensure good drainage to prevent waterlogging.

Prune to maintain shape and remove any dead, damaged, or crossing stems. Pruning can be done after flowering or at the beginning of the growing season. Wear gloves as the sap can be irritating.

Remove any leggy growth to encourage a more compact form.

Propagate from stem cuttings taken in spring or summer. Allow the cuttings to callus for a few days to a week before planting in well-draining soil. Water sparingly until roots form.

This method is generally successful for this species.

Repot only when the plant becomes root-bound, typically every 2-3 years. Use a gritty, fast-draining potting mix, such as a cactus or succulent blend. Repot in spring before the active growing season begins.

Water lightly after repotting.