Sacred Datura thrives with moderate watering. Allow the soil to dry out slightly between waterings, especially during the growing season. Reduce watering significantly in winter to prevent root rot.

Overwatering is a common mistake; ensure good drainage to keep the roots healthy.

Prune Sacred Datura in late winter or early spring before new growth begins. Remove any dead, damaged, or crossing branches. This also helps maintain a desirable shape and size.

Lightly trim back overgrown stems to encourage bushier growth and more blooms.

Propagation is typically done through seeds sown in spring, or by taking semi-hardwood cuttings in summer. Seeds may require scarification or stratification.

Cuttings should be rooted in a well-draining potting mix under humid conditions, with bottom heat providing the best results.

Repot Sacred Datura every 2-3 years, or when it becomes root-bound. Spring is the ideal time for repotting, just as new growth begins.

Use a well-draining potting mix and a pot that is only slightly larger than the previous one to avoid excessive moisture retention.