Water thoroughly when the top 2-3 cm of soil feel dry. Allow the soil to dry out slightly between waterings, as Silybum eburneum is drought-tolerant once established. Avoid overwatering, which can lead to root rot.

Reduce watering in cooler months.

Pruning is generally not required for Silybum eburneum beyond removing spent flower stalks or dead foliage. If it becomes too large, it can be cut back after flowering to maintain shape, but this is rarely necessary.

Propagation is typically done by seed. Sow seeds in early spring, either directly outdoors after the last frost or indoors a few weeks prior. Seeds germinate readily under suitable conditions.

Repotting is usually only necessary if the plant becomes root-bound, which is uncommon for this species as it often self-seeds. If repotting is needed, do so in spring using well-draining soil.