Water deeply but infrequently, allowing the soil to dry out completely between waterings. Overwatering can lead to root rot. Reduce watering significantly during the dormant winter months to mimic natural dry periods.

Pruning is generally not required for Strychnos pungens, as it maintains a compact, shrubby habit. If necessary, prune to remove dead or damaged branches.

Minimal pruning will help maintain its natural form and encourage flowering.

Propagation is best achieved through seeds, which require scarification and a period of stratification. Sow seeds in a well-draining seedling mix and keep consistently moist and warm. Cuttings are difficult to root.

Repot young plants every 2-3 years in spring. Mature plants are slow-growing and rarely need repotting. Use a well-draining potting mix, such as a cactus or succulent blend. Avoid disturbing the roots excessively.