Water thoroughly when the soil is completely dry. Overwatering is the most common cause of rot for Stapelia grandiflora. Reduce watering significantly during the winter dormancy period to prevent root rot.

Ensure good drainage to avoid waterlogged conditions.

Pruning is mainly for aesthetic purposes and to manage size. Remove any dead, damaged, or diseased stems promptly. You can also trim back overgrown stems to encourage bushier growth.

Use clean, sharp tools to make clean cuts and prevent disease spread.

Propagate Stapelia grandiflora from stem cuttings. Allow cuttings to callus for a few days before planting in well-draining soil. Roots typically form within a few weeks.

It can also be grown from seed, but this is a slower method.

Repot every 2-3 years or when the plant outgrows its container. Choose a pot with drainage holes and use a well-draining cactus or succulent mix.

Repot in spring before the active growing season begins to minimize stress on the plant.