Water regularly, allowing the soil to dry slightly between waterings. Ensure good drainage to prevent waterlogged conditions, which can lead to root rot.

Reduce watering frequency during winter months when the plant's growth slows down.

Pruning is generally not necessary for Dysphania atriplicifolia. If the plant becomes too leggy or overgrown, it can be trimmed back in spring to encourage bushier growth. Remove any dead or damaged foliage as needed.

Propagate from seed sown in spring, either directly outdoors or started indoors a few weeks prior. Seeds germinate readily in warm conditions.

Cuttings can also be taken in late spring or early summer and rooted in moist soil.

Repot young plants annually or biennially in spring as needed, preferably into a slightly larger container. Established plants are often best left undisturbed. Ensure the new pot has adequate drainage holes.