Water thoroughly when the top 2-3 cm of soil is dry. Adenia penangiana prefers to dry out slightly between waterings. Reduce watering significantly during the winter dormancy period to prevent root rot.

Ensure excellent drainage to avoid waterlogged conditions.

Prune to shape the plant and manage its size, typically in late winter or early spring before new growth begins. Remove any dead, damaged, or crossing branches. This vigorous climber can become unruly if not managed.

Propagate from stem cuttings taken during the growing season. Allow cuttings to callus for a few days before planting in a well-draining potting mix. Rooting can be slow, so patience is key.

Some sources suggest propagation from seed, but cuttings are more common.

Repot young plants every 1-2 years, and mature plants less frequently, typically when root-bound. Use a fast-draining potting mix, such as a cactus or succulent blend. Repot in spring, just as new growth appears.

Ensure the new pot has drainage holes.