Water regularly during the growing season, allowing the soil to dry slightly between waterings. Reduce watering significantly in winter.

Desmanthus virgatus is drought-tolerant once established, so avoid overwatering, which can lead to root rot.

Prune in late winter or early spring to shape the plant and remove any dead or damaged branches. Light pruning throughout the growing season can encourage bushier growth and more flowers.

Deadheading spent blooms can also promote further flowering.

Propagate by seeds, which germinate readily after scarification or soaking. Cuttings can also be taken from semi-hardwood in summer and rooted in moist soil or a well-draining medium.

Repot young plants annually or biennially in spring. Mature plants can be repotted less frequently, only when root-bound. Use a well-draining potting mix, such as a cactus or succulent mix, to prevent waterlogging.