Keep the soil consistently moist but not waterlogged, especially during active growth. Reduce watering slightly in cooler months. Check the soil moisture by touching the surface; water when the top 2-3 cm feels dry.

Overwatering can lead to root rot, so good drainage is essential.

Prune to maintain desired shape and size, and to encourage bushier growth. Remove any dead, damaged, or leggy stems as needed.

Light pruning can be done anytime, but heavier pruning is best performed in late winter or early spring before new growth begins.

Propagate Melothria dulcis from seeds sown in spring, or by taking stem cuttings in late spring or early summer. Seeds should be sown in a well-draining seed-starting mix and kept moist.

Cuttings should be rooted in a similar medium and kept in a warm, humid environment.

Repot young plants annually in spring, and mature plants every 2-3 years or when root-bound. Use a well-draining potting mix. Choose a pot that is only slightly larger than the current one to avoid overwatering issues.

Water thoroughly after repotting.