Melothria pendula prefers consistently moist soil. Water thoroughly when the top 2-3 cm of soil feels dry to the touch. Avoid waterlogged conditions, which can lead to root rot.

In hot weather, more frequent watering may be necessary to maintain adequate moisture levels.

Pruning is generally not required for Melothria pendula unless it becomes overgrown or diseased. If pruning is needed, remove dead, damaged, or crossing branches. Light pinching of tips can encourage bushier growth.

Prune in late winter or early spring before new growth begins.

Propagate Melothria pendula from seeds sown indoors in early spring, about 4-6 weeks before the last frost. Seeds can also be direct sown outdoors after the danger of frost has passed.

Cuttings can be taken from healthy stems in late spring or early summer.

Repot Melothria pendula annually or when it becomes root-bound. Choose a pot that is slightly larger than the current one, with good drainage. Use a well-draining potting mix.

Repot in early spring before the active growing season begins to minimize stress.