Allow the soil to dry out completely between waterings. Cnidoscolus aconitifolius is drought-tolerant once established. Overwatering can lead to root rot, so ensure good drainage.

Reduce watering significantly during cooler months or when the plant is dormant.

Prune to maintain shape and size, or to remove dead or damaged branches. This can be done anytime, but major pruning is best in late winter or early spring before new growth begins.

Pinching back young shoots encourages bushier growth.

Easily propagated from stem cuttings. Take 10-15 cm cuttings from healthy stems, allow them to callus for a few days, then plant them in well-draining soil. Keep them warm and lightly moist until roots form.

Repot only when root-bound, typically every 2-3 years. Use a well-draining potting mix. Choose a pot that is only slightly larger than the current one.

Repot in spring before active growth begins to minimize transplant shock.